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All eyes turn for a fascinating Premier League matchup as table-toppers Arsenal host bottom-placed Wolverhampton Wanderers to the Emirates Stadium.

Confirmed Sides

Mikel Arteta's side have made three changes following the team that endured a 2-1 defeat at Aston Villa in their previous outing. William Saliba, Viktor Gyökeres and Gabriel Martinelli all start in the lineup. Martin Ødegaard and the Spanish midfielder are named on the bench, while Riccardo Calafiori is absent. The centre-back is back after missing five matches due to injury.

The visitors also make three adjustments to their lineup following being skelped 4-1 at home by United on Monday evening. The experienced full-back, João Gomes and Hwang Hee-chan start. Ki-Jana Hoever and Jhon Arias drop to the bench, while Jean‐Ricner Bellegarde is not in the squad altogether.

Confirmed Lineups

Arsenal: Raya, White, Saliba, Hincapie, Timber, Eze, Zubimendi, Rice, Saka, Gyokeres, Martinelli.
Substitutes: Arrizabalaga, Odegaard, Gabriel Jesus, Norgaard, Trossard, Madueke, Nwaneri, Merino, Lewis-Skelly.

Wolverhampton Wanderers: Johnstone, Mosquera, Agbadou, Toti Gomes, Doherty, Joao Gomes, Andre Trindade, Krejci, Wolfe, Larsen, Hwang.
Subs: Tchatchoua, Mane, Lopez, Hoever, Chirewa, Arokodare, Arias, Santiago Bueno, Jose Sa.

Referee: Robert Jones
Video Assistant Referee: John Brooks

The Setup

Welcome! Because, look at this …

The standings paints a clear story. The hosts sit comfortably at the summit of the table, while their opponents prop up the division.

… however, even though this will be the 42nd occasion the Premier League leaders have played the team at the foot of the division – with 30 victories from 41, with seven draws – which team is behind two of the four all-time upsets? Indeed, Wolves, of course! So while the Arsenal manager will undoubtedly be anticipating another victory, the Wolves boss must know that underdogs sometimes find the target, and you never know. Kick-off is at 8 o'clock in the evening GMT. It’s on!

^{(The other two last-over-first victories in the Premier League era are Oldham’s 1-0 win over United in March 1993, and Spurs – yeah, this one sounds a bit weird - beating Liverpool in November 2008.)}